Hadn't heard of it until just now - but looks like a stack built on MapServer and OpenLayers to provide web mapping. What are you hoping to do with it?
Forming a team to respond to an RFQ. Establish a GIS for a small city hereabouts. Another local city recently established a GIS based on GeoMoose and one of the team members is hot for it.
Something like GeoMoose would serve smaller municipalities quite nicely and would make a great scalable and replicatable model to market to other communities. The only real hurdle would be the initial one of getting some familiarity with it, but the basics of wrangling data between GIS and CAD formats, dealing with datums and other stuff that's not rocket science for surveyors, plus spatial databases and other things are in most cases transferrable between open source, ESRI, Oracle Spatial and others.
Yeah... GeoMoose is a great program although there's the minor problem of the difficulty when first using it. If you're the type who picks up quickly when it comes to these kinds of programs, you should be okay. On second thought, I think most GIS programs are quite hard to figure out on the initial use.